Proteins are the workhorses of cells and are responsible for transport, storage, movement, recognition, signal transduction, protection (antibodies), energy storage, metabolism, and structure. Understanding protein structure is the first step in understanding their functions. In addition, understanding how proteins interact with other molecules in the cell is crucial for understanding protein functions. This 4 half-day workshop aims to familiarize you with sources of experimental and theoretical protein structure models and one or more visualization software programs.
Day 1 - Investigate Protein Data Bank (PDB) together (introduction to proteins)
Day 2- We will learn the PDB file structure.
Day 3- We will visualize proteins from the PDB files using Chimera X.
Day 4- We will identify different categories of secondary structures through visualization.
This workshop will be beneficial anyone who is interested in molecular structures or function with applications in biology, chemistry, physics, computer science, or engineering. Successful completion of this workshop provides a foundation for protein modeling, ligand complex modeling, molecular dynamics and computer aided drug design.
When you complete this workshop successfully, you will be able to:
- Identify secondary structure and backbone conformation of proteins.
- Identify and use various online resources to gather protein structure information.
- Gain practice using PDB file format.
- Create protein structure data representations and visualizations using ChimeraX.
This course applies toward the Bioinformatics Endeavor digital badge.