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Course Description

Immunology taught me that germs are bad, so why do I feel sick when I take antibiotics? What’s a monoclonal antibody? Why is transplantation so complicated?” If you’ve found yourself wondering these questions, which are typically beyond the scope of an introductory immunology course, this is the perfect course for you. IMMU 420 builds upon the foundations laid in introductory immunology courses such as IMMU 403. We explore concepts such as auto-immunity, transplantation, and mucosal immunity while also introducing the concept of host pathogen interactions: pathogenic and beneficial. We also discuss therapeutic modulators of the immune system, common laboratory techniques as practical applications of the immune concepts covered.

Learning objectives:

  • Identify and discuss the mechanisms used by natural killer cells to guard against infection throughout the body. Discuss the role of NK cells in innate immune defenses at various tissue sites.
  • Compare and contrast the players of mucosal immunity versus systemic immunity to distinguish the difference between infections and vaccines at mucosal surfaces.
  • Distinguish between and classify various types of autoimmune diseases.
  • Predict the outcome of transplantation after examination of various histocompatibility markers. Predict how various histocompatibility markers can adversely affect transplantation.
  • Devise a treatment plan for hypothetical patients with autoimmune diseases based on student knowledge of immune modulating drugs.
  • Discuss some of the ways the microbiome influences the immune system of the host.
  • Set up theoretical experiments using common immune system experimental protocols to test provided hypotheses.

Prerequisites, IMMU403 or a solid foundation in immunology

Target audience: Any students of IMMU403 who want to expand their knowledge of the immune system as well as interested post-baccalaureate or postdoctoral researcher fellows who want to learn specific advanced immunology concepts.

 

Textbook Information

There is a recommended textbook for IMMU 420 that can be purchased through FAES or on your own. The name of the book is The Immune System, 5th ed. The fee for the book is $179.00.  If you would like to purchase the book through FAES, please register for the section that includes the book.  Upon receipt of payment and fulfillment of your book order, your book can be picked up at the FAES Bookstore in Building 10 on the NIH campus in Bethesda.

If you are unable to pick up the book at the FAES bookstore and would like the book mailed to you, please contact FAES at (301) 496-7976 or registrar@faes.org.  There is an $11 charge for mailing the book.

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Section Title
Advanced Immunology and Host Microbe Interactions
Type
Online Asynchronous
Dates
Jun 15, 2022 to Aug 02, 2022
Delivery Options
Fee (Includes Tuition and Technology Fee)
Eligible Discounts Can Be Applied at Checkout credit (2 Credits) $625.00
Potential Discount(s)
Available for Academic Credit
2 Credit(s)
Section Title
Advanced Immunology and Host Microbe Interactions (WITH RECOMMENDED BOOK)
Type
Online Asynchronous
Dates
Jun 15, 2022 to Aug 02, 2022
Delivery Options
Fee (Includes Tuition and Technology Fee)
Eligible Discounts Can Be Applied at Checkout credit (2 Credits) $812.00
Potential Discount(s)
Available for Academic Credit
2 Credit(s)
Section Materials
  • (Optional) The Immune System by Parham, Peter W. W. Norton 5th edition $187.00 ISBN 9780393533354 FAES Bookstore
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