Course Description

Please note that this is a 14-week course offered in partnership with NHGRI, which includes live sessions Thursdays, 5:30-7:30 PM ET

The course will cover basic and advanced concepts in cancer genomics and will address practice guidelines created and adopted by authoritative resources such as ACMG, AMP, ASCO and NCCN. The major focus will be on the applications of cytogenetic and molecular genetics in the diagnosis, prognosis and therapeutics. The didactic and core lectures will be supplemented by clinical case discussion in germline genetics, hematopathology and solid tumors.

Learner Outcomes

When you complete the course successfully, you will be able to:

Somatic Cancers

• Describe the use of cytogenetics in somatic cancer
• Describe molecular profiling in somatic cancer
• Describe variants using appropriate nomenclature
• Interpret variants according to standardized criterion

Hereditary Cancers

• Describe the pathogenesis of the most common inherited cancer syndromes
• Describe the methods for detection and interpretation of results for the disorders
• Describe variants using appropriate nomenclature
• Interpret variants according to standardized criterion
• Discuss detection as secondary findings of NGS testing

Target audience: Laboratory Genetics and Genomics (LGG fellows) and others seeking Certification by the American Board of Medical Genetics and Genomics

Textbook Information

There is no textbook for purchase required for this course.