The goal of this course is to provide students with an overview of tools, methods, and concepts used in the broad sphere of computational genomics.  Although we will use tools occasionally, the primary focus of materials will guide students to learn about available computational strategies and how, why, and when to use them.  Whenever students are asked to use tools, they will be point-and-click applications that do not require coding.  After taking this course and learning about the breadth of topics under the umbrella of computational genomics, students will be well-equipped to decide which more advanced topics to study to deepen their knowledge and learn relevant skills.  Specific topics covered will include genome-wide association studies (GWAS), variant detection, next-generation sequencing including single-cell RNAseq, comparative genomics, and cross-species evolution-based analyses.