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Course Description

The immune system encompasses a broad, highly interactive network of cells, tissues, and anatomical structures that protects us from infection and cancer, yet can also induce autoimmune disease. The course will explore the genetics, cell biology, and physiology that govern both our resistance to infection and the induction of autoimmune disease and allergy. Distinctions between the innate/natural immune system and the adaptive immune system will be discussed. The role of intestinal microbiota, inflammatory reactions, and vaccines will be also studied. Central to the discussions will be the role of cellular subsets (B cells, T cells, macrophages), serum proteins (immunoglobulins and complement), and cell surface receptors whose coordinated activities comprise the immune response. Specific immune pathologies or deficiencies associated with human disease will be also highlighted.

Prerequisites:

Familiarity with cell biology.

Credentials:

This course applies toward the Advanced Cancer Biology Discovery Badge interdisciplinary badge.

 

 

 

 

 

Learning Objectives:

  • Summarize key cellular components of the immune response.
  • Distinguish the function of innate/natural and adaptive immune systems.
  • Recall how the key antigen recognition molecules (TCR, BCR) arise from genetic recombination, and how the specificity of the immune repertoire is shaped.
  • Discuss the role of inflammation during infection, autoimmunity, and cancer.
  • Illustrate how cytokine activity affects cell signaling and function.
  • Predict how the immune system plays a role in the resistance to infection, induction of allergies, autoimmunity, and cancer.

Textbook Information

There is a required textbook for IMMU 403 that can be purchased through FAES or on your own. The name of the book is The Immune System, 5th ed. The fee for the book is $178.75.  If you would like to purchase the book through FAES, please register for the section that includes the book.  Upon receipt of payment and fulfillment of your book order, your book can be picked up at the FAES Bookstore in Building 10 on the NIH campus in Bethesda.

If you are unable to pick up the book at the FAES bookstore and would like the book mailed to you, please contact FAES at (301) 496-7976 or registrar@faes.org.  There is a $10 charge for mailing the book.

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Section Title
Basic Principles of Immunology and Hypersensitivity
Type
Online Asynchronous
Dates
Oct 25, 2021 to Dec 10, 2021
Fee (Includes Tuition and Technology Fee)
Eligible Discounts Can Be Applied at Checkout credit (2 units) $625.00
Potential Discount(s)
Available for Credit
2 units
Instructors
  • Ragavan Varadharajan Suresh
Section Title
Basic Principles of Immunology and Hypersensitivity (WITH REQUIRED BOOK)
Type
Online Asynchronous
Dates
Oct 25, 2021 to Dec 10, 2021
Fee (Includes Tuition and Technology Fee)
Eligible Discounts Can Be Applied at Checkout credit (2 units) $803.75
Potential Discount(s)
Available for Credit
2 units
Instructors
  • Ragavan Varadharajan Suresh
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