BIOL 425 - Principles and Applications of CRISPR

Course Description

This course provides a comprehensive overview of CRISPR-Cas9, a groundbreaking gene-editing technology that has revolutionized biological research and holds immense potential for therapeutic applications. CRISPR-Cas9, derived from a bacterial adaptive immune system, utilizes a programmable RNA guide to direct the Cas9 nuclease to a specific DNA sequence for cleavage and subsequent modification. By the conclusion of this course, students will be well-versed in the concepts, principle, and experimental procedures of CRISPR-Cas9 technology, as well as its wide-ranging applications in biomedical research.

Learner Outcomes

When you complete the course successfully, you will be able to:

Develop a thorough understanding of the principles underlying CRISPR gene-editing technology.
Analyze and compare different methods for introducing CRISPR components into cells, considering their advantages and limitations.
Identify and compare the various applications of CRISPR technology across diverse experimental contexts.
Utilize CRISPR-based genome-wide screens, in conjunction with bioinformatic analysis, to apply in scientific research.
Critically assess the current and potential future applications of CRISPR gene editing in treating human diseases, including associated challenges and ethical considerations.

Microcredential(s)

This course applies toward the Biomedical Sciences Curiosity interdisciplinary badge.

Textbook Information

There is no textbook for purchase required for this course.

Prerequisites

Basic understanding of molecular biology and cell biology.

Refund
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