FAES Science Insight Series

This series invites Principal Investigators, Senior Scientists, and Senior Clinicians to share cutting-edge research and developments in their fields. This is an in person event held in the FAES Learning Labs in Building 10 located on the NIH Main Campus in Bethesda, MD and is only for members of the NIH community. 

 

Upcoming Science Insight Events

Diagnosing and Managing Diabetes: Where the Clinical Lab Meets Patient Care
June 12, 2025 from 11:45AM to 1:00PM

Speaker: David Sacks, MB ChB, FACP, FRCPath, Senior Investigator and Chief of Clinical Chemistry, Department of Lab Medicine, Clinical Center

Diabetes is estimated to affect more than 500 million adults, half of whom are not diagnosed. The integral role of the clinical laboratory in both the diagnosis and monitoring of diabetes will be addressed using evidence-based guidelines.

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Past Science Insight Events

AI in Medicine: Focus on Deep Learning in Medical Genomics  
January 23, 2025 from 12:00 – 1:00 pm ET

Speaker: Dr. Benjamin Solomon (MEDI 505)

AI is already dramatically changing biomedical research and the practice of medicine. Using the field of medical genomics as an example, this talk will (relatively informally) describe how deep learning, a particularly powerful type of AI, is used and studied.

Bringing Gene Therapy to the Clinic for Sickle Cell Disease 
February 25, 2025 from 11:45 – 1:00 pm ET

Speaker: John Tisdale, M.D. Senior Investigator, NHLBI

Advances in gene editing, including lentiviral vectors and in vivo approaches, are revolutionizing treatment possibilities. Lentiviral-based gene transfer significantly reduces pain and hospitalizations, while innovations like CD117-targeting antibody-drug conjugates eliminate chemotherapy in bone marrow ablation. Ongoing research focuses on enhancing delivery systems to efficiently target hematopoietic stem cells for lasting therapeutic benefits.

Expecting the Unexpected: Erythropoietin Beyond Red Blood Cell Production  
March 27, 2025 from 11:45 – 1:00 pm ET

Connie Noguchi, Ph.D., Acting Branch Chief, NIDDK

Erythropoietin is known for treatment of anemia to increase erythrocyte production. Additionally, animal models demonstrate receptor mediated erythropoietin metabolic and stress response including protective activity in brain, cardiovasculature, skeletal muscle, and obesity, suggesting the therapeutic potential of erythropoietin beyond erythropoiesis.

Immunology on a WHIM
April 15, 2025 from 11:45 – 1:00 pm ET

Philip M. Murphy, M.D., Senior Investigator, NIAID

Inborn errors of immunity provide an opportunity to help rare patients with devastating diseases as well as to unlock immunological principles that might be generalized to more common conditions.  WHIM syndrome is an inborn error of immunity caused by gain-of-function mutations in the chemokine receptor CXCR4 where new insights about pathogenesis have led to new concepts for drug treatment, as well as cure through gene therapy and allotransplantation.

The Air Makes Me Flare: How the Environment is Causing the Allergy Pandemic
May 06, 2025 from 11:45AM to 1:00PM

Speaker:  Ian A. Myles, M.D., M.P.H., Principal Investigator, Epithelial Therapeutics Unit, NIAID

We will discuss the evidence for why the modern rise of allergic disease is tied to industrial exposures, outline the specific exposures of concern, and discuss what we can do to combat the harms.

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